Generation of the first autofluorescent Vaccinia virus

Following collaboration with Transgene, a biotechnology company focused on discovering and developing targeted immunotherapies for the treatment of cancers and infectious diseases, we have validated the first poxvirus where the viral DNA is autofluorescent: the ANCHOR Vaccinia Virus (VV DNA in red). Treatments based on Vaccinia Viruses are among Transgene’s lead products. This virus can now be used to understand the behavior of oncolytic vectors and for screening applications in living cells. Microscopy data generated by autofluorescent viruses are a tremendous asset for communication/investor/media. More information:,