In the New Year, we'll be putting out more of our ANCHOR viruses to answer all your questions!
Whether you're developing antivirals, physical or chemical disinfection systems, oncolytic viruses or need high-throughput imaging and analysis, don't hesitate to contact us!
Picture (art) of the month, January 2023.
Human cells infected with VACV ANCHOR poxvirus (green: infected cells, green
dots: viral DNA) and stained with WGA 555 (Magenta) and DAPI (blue) 20h
post infection. Cells acquired on CellInsight CX7 at 60X, camera full chip. We wish you a colorful year !
SARS-CoV-2 infecting human pulmonary cells 48h post-infection, nuclei in blue, SARS-CoV-2 RNA in green, SARS-CoV-2 NP in red. Work done by Charlotte Quentin-Froignant.
Orthopoxvirus titration using high resolution imaging. Cells are infected with serial dilution of VACV and stained with crystal violet. Following fixation, 24 well plate is scanned on Thermo Fisher Scientific CX7 Cellinsight.
Picture is a reconstruction of 374 fields, 3 picture /field (R/G/B) and displayed in real color. It took 5 min to acquire the 1122 images and reconstruct the full well. Is it useful in routine ? Of course not. Is it cool ? Indeed 🙂
Picture of the month,
July 2022. Duodenum organoids in culture stained for nuclei (blue) and
cytoskeleton (green and red). Ready to be infected by an ANCHOR tagged
virus. Work in collaboration with Stephane Bertagnoli and Adrien Lion from the Ecole Nationale Vétérinaire de Toulouse. Image reconstruction from a 3 channel Z stack taken in confocal mode on a Cell Insight CX7 HCS microscope from Thermo Fisher Scientific
Purification of a recombinant influenza H1N1 virus expressing a fluorescent protein. Nuclei in blue, infected cells in yellow. We thought the color code is appropriated. Work by Thomas Figueroa and Quentin Husson.
We have been mandated by a company to test disinfection procedure on several class of viruses. 2 engineers doing the experiment in our BSL2+ laboratory. Results have shown a >3log10 decrease in infectious viruses using the decontamination procedure of our customer.
